University College of Science was established as intermediate college in 1922 by Udaipur’s Maharana “Maharana Bhupal Singh Ji”. Later in 1945 it was upgraded to Degree College as "Maharana Bhupal College". In 1962, Maharana Bhupal College now known as University College of Science was merged with the Udaipur University (now Mohanlal Sukhadia University) as a constituent college. Subsequently, five PG departments namely Botany, Chemistry, Mathematics, Physics and Zoology were established in 1964 to provide teaching in co-education mode. The college played pivotal role in starting Computer Science as optional subject in B.Sc. in 1985. UG in Environmental Science, PG in Statistics and PG in Polymer Science started in 1990. In continuation of faculty expansion, the B. Pharm. was started in Department of Pharmaceutical Sciences in 1998. In addition to imparting education in all the science subjects, self-?nanced BCA, B.Sc. and M.Sc. in Biotechnology are also operational.  With the objective to promote employability many professional programmes like B. Pharm., BCA, M.Sc. Tech (Geology), Polymer Science offering skill enhancement courses are being run at present. More than 3500 students are currently enrolled in this college.